Chronic kidney disease, uremic milieu, and its effects on gut bacterial microbiota dysbiosis
نویسندگان
چکیده
منابع مشابه
Dysbiosis of the gut microbiota in disease
There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular disease, and obesity.
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Inflammation is a multifactorial phenotype that in chronic kidney disease is associated with adverse patient outcomes. Recently, alterations in gut microbiota composition and intestinal barrier have been associated with inflammation and oxidative stress in CKD patients. Vanholder and Glorieux recently critically reviewed [Clin Kidney J (2015) 8 (2): 168-179] the current understanding of the rol...
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Antibiotics are often prescribed inappropriately to infants and young children, with potentially adverse effects on the developing gut microbiota and related metabolic processes. We review evidence from 17 epidemiologic studies suggesting that antibiotic exposure during critical periods of early development may influence weight gain and the development of obesity. Complementary research in both...
متن کاملHuman Gut Microbiota: Dysbiosis and Manipulation
The adult human intestine is home to an almost inconceivable number of microorganisms. Their population is up to 100 trillion, nearly 10 times larger than the total number of our somatic and germ cells. All three domains, including bacteria, archaea, and eukarya, are contained in the adult human gastrointestinal (GI) tract and the bacteria achieve the highest cell densities and phylogenetic div...
متن کاملRetraction: Human gut microbiota: dysbiosis and manipulation
The authors and the journal wish to retract the 27 September 2012 article cited above. Based on information discovered after publication and reported to the journal in November 2013, this article was found to contain sections that were taken verbatim from other sources without giving proper reference to the source and without identifying the citation as a word-by-word citation from that source....
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2018
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00092.2018